Many manufacturing technologies follow a similar journey.
They begin with grams in the laboratory, advance through kilograms in process development, and ultimately succeed only when they can be manufactured reliably at the ton scale.
Our Body Armor for Enzymes™ technology is no different.
Much of the conversation surrounding biocatalysis focuses on enzyme discovery, protein engineering, and reaction optimization. These advances continue to expand what enzymes can accomplish, opening new opportunities across pharmaceuticals, food ingredients, specialty chemicals, personal care, and sustainable manufacturing. Yet innovative enzymes alone are not enough.
Turning promising laboratory results into commercial manufacturing requires an equally important foundation: robust and economical processes, which our biocatalysts help enable, and now, at an increased scale.
As the product of a collaboration between our team and Technip Energies’ Advanced Materials & Catalysts business , we have successfully completed our first 10 kg production run of Cascade Bio's proprietary Body Armor for Enzymes™ immobilization resin.
Building the Foundation
Over the past several years, Technip Energies has been an important partner as we've developed our immobilization resins starting from milligrams.
Their expertise in silica materials and industrial manufacturing, and their hands-on collaboration in tuning support properties to our coating chemistry, has provided a scalable foundation for our platform.
The Technip Energies team contributes deep experience developing and manufacturing silica materials at scale. Cascade Bio contributes proprietary immobilization chemistry designed to expand the range of enzymes that can be deployed in demanding manufacturing environments.
Neither capability replaces the other. Together, we create something greater than either could achieve independently.
Why 10 kg Matters
A successful 10 kg production campaign represents far more than producing additional material.
Every increase in manufacturing scale introduces new challenges. Materials must remain consistent. Processes must become more robust. Quality expectations become more demanding. Manufacturing transitions from laboratory experimentation toward repeatable production.
Each successful step builds confidence for the next.
For Cascade Bio, this production run represents an important milestone as we continue preparing our platform forlarger customer programs and future commercial manufacturing.
Looking Toward Ton-Scale Manufacturing
Our vision extends well beyond 10 kg.
To deliver on larger customer applications, we’ll have to be manufacturing at the ton scale. Achieving that goal demands more than breakthrough chemistry. It requires manufacturing expertise, reliable supply chains, and long-term partnerships built around shared success.
The journey from grams to kilograms, from kilograms to tens of kilograms, and ultimately to tons cannot be accomplished alone.
It requires established manufacturing partners willing to work alongside emerging technology companies, combining decades of industrial experience with new scientific approaches.
We're excited to continue working alongside Technip Energies as we scale our platform from grams, to kilograms, to tens of kilograms, and ultimately toward ton-scale manufacturing, helping scale our immobilization technology to unlock more enzymes and expand the role of biocatalysis across the industries that rely on chemistry every day.
To learn more about Technip Energies Advanced Materials & Catalysts please visit: https://www.ten.com/en/products-and-services/advanced-materials-and-catalysts
